While BCAA supplementation may be useful
for gaining skeletal muscle. A BCAA supplement is especially helpful for
maintaining mass while on a calorie-deficit diet. They're particularly useful
for bodybuilding competitors who take their physiques to the lean extreme. Although dieting down makes you look awesome
onstage, on the beach, and to your friends, it can also take a chunk out of
your muscle mass. Increased BCAA levels also work in your favor by reducing the
rate of protein breakdown. They do this by decreasing the activity of the
protein breakdown pathway, and also by decreasing the expression of several
complexes involved in protein breakdown. There are three BCAAs: leucine,
isoleucine, and valine, which are all essential amino acids not produced by the
body but needed for survival. BCAAs are the largest collection of amino acids
in the body, accounting for up to 35% of muscle proteins. Basically, a BCAA supplement
are excreted rapidly. BCAA intermediates can be toxic at high concentrations,
so functional BCAA breakdown is vital. BCAA formulas have been on the market
since 1996, mainly for treating liver diseases such as cirrhosis and
hypoalbuminemia. Nowadays, BCAAs are mainly used by bodybuilders for exercise
purposes, to increase energy, and to boost protein synthesis. Another
interesting BCAA benefit is delayed fatigue during prolonged exercise, allowing
you to work harder, longer. This study shows that BCAAs may help keep you
focused and alert by blocking tryptophan from crossing the blood-brain barrier a
process that normally increases during extended exercise, and is followed by
serotonin production, which causes fatigue. Additionally,
to the recovery benefits, that improved mental edge which is critical during
strategic, grueling, long-distance events—is why BCAAs are widely used among
endurance athletes like ultra-runners and triathletes.
Some people use branched-chain amino acids
to prevent fatigue and improve concentration. Athletes use branched-chain amino
acids to improve exercise performance and reduce protein and muscle breakdown
during intense exercise. Healthcare providers give branched-chain amino acids
intravenously (by IV) for sudden brain swelling due to liver disease (acute
hepatic encephalopathy) and also when the body has been under extreme stress,
for example after serious injury or widespread infection. Branched-chain amino
acids stimulate the building of protein in muscle and possibly reduce muscle
breakdown. Branched-chain amino acids seem to prevent faulty message
transmission in the brain cells of people with advanced liver disease, mania,
tardive dyskinesia, and anorexia. Despite all these benefits of BCAA
supplementation, there are many skeptics who say branched-chain amino acids are
overpriced and you can just get them from whey protein. While proteins like
whey are naturally rich in BCAAs, this isn't the most effective strategy for
muscle growth or fat loss. The BCAAs in whey are peptide-bound to other amino
acids. In order to raise BCAA levels in your body, they must be liberated
through digestion and then absorbed into the bloodstream. Even though whey protein
is relatively fast digesting, it still takes several hours for all the amino
acids to be broken down and absorbed into the plasma. Branched-chain amino
acids in supplement form, however, are free-form, require no digestion, and are
rapidly absorbed into the bloodstream. They spike blood amino acid levels more
quickly and to a much greater extent than peptide-bound amino in proteins. Even
a few grams of free-form BCAAs will spike BCAA plasma levels way more than 30
grams of whey protein. They can start working right away.
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